BMC Cell Biology | Full text | Long term culture of mesenchymal stem cells in hypoxia promotes a gen In the bone marrow, hematopietic and mesenchymal stem cells form a unique niche in which the oxygen tension is low. Hypoxia may have a role in maintaining stem cell fate, self renewal and multipotency. However, whereas most studies addressed the effect of
Mesenchymal stem cells and their microenvironment. Front Biosci (Landmark Ed). 2011 Jun 1;16:2271-88. Mesenchymal stem cells and their microenvironment. Schraufstatter IU, Discipio RG, Khaldoyanidi S.
Bone marrow-derived mesenchymal stem cells and the tumor ... However, the nature of the relationship between MSC and tumor cells appears dual. Primary and metastatic tumors attract MSC in their microenvironment where ...
Engineering microenvironments to control stem cell fate and function ... Accordingly, the identification of extrinsic factors and their downstream, ... In a recent example involving human and porcine mesenchymal stem cells (MSCs), ...
Manipulation of Stem Cells and their Microenvironment for Tissue ... 2013年6月25日 - Scaffold; Mesenchymal stem cells; Adipose-derived stem cells; ... cells and their specialized microenvironment, known as the niche, will.
Microenvironmental considerations in the application of human ... Keywords: cytokine, microenvironment, mesenchymal stem cells, bone marrow. Introduction ... the possibility of tumor formation has caused their application.
Mesenchymal stem cells and their microenvironment. - ResearchGate ABSTRACT Mesenchymal stem cells (MSC) are multipotent stem cells that hold promise for an expanding list of therapeutic uses, not only due to their ability to ...
Rewiring mesenchymal stem cell lineage specification by switching ... 2014年6月5日 - We chose to explore two diverse differentiation outcomes: MSC osteogenesis ... Cells sense their mechanical microenvironment through the ...
Mesenchymal stem cells: environmentally responsive therapeutics ... 2013年11月15日 - Mesenchymal stem cells (MSCs) are partially defined by their ability ... at variable concentrations in response to local microenvironmental cues.
Mesenchymal stem cells in the tumor microenvironment (Review) 2013年5月10日 - Mesenchymal stem cells (MSCs) are pluripotent cells that give rise to a ... microenvironment were identified as EGFP-positive, indicating their ...